Here's a little bit of weirdness for you. I have arthritis in my neck and can't look up, barely horizontal. I struggled for years using a desktop, the struggle being that it just hurt.
I bought a decent laptop, I won't say what, but I am so glad I'm not contributing to Bill Gate's retirement fund, and do all my work with it actually in my lap while sitting in a comfortable overstuffed chair with my feet on the coffee table, looking down at it.
I spend a lot of time on my LT: bookkeeping, correspondence, business management, writing, research, and am so happy I stumbled on this comfortable solution to my peculiar handicap.